ROTAGAL

One dose of the vaccine (3 ml) contains:

Active substance:

Bovine rotavirus strain TM-91, serotype G6P1 (inactivated)       

2/3 dose of vaccine inducing ≥ 6,0 log2 (VNT), *

Bovine coronavirus strain C-197 (inactivated)          

2/3 dose of vaccine inducing ≥ 5,0 log2 (HIT) **

Escherichia coli strain EC/17 (inactivated) expressing F5 (K99) Adhesin

2/3 dose of vaccine inducing ≥ 44,8 % of inhibition (ELISA)***

* VNT – virus neutralisation test

**HIT –          hemagglutination inhibition test

For active immunization of pregnant cows and heifers to provide calves with passive immunity targeted at reduction of mortality, incidence and severity of diarrhoea caused by bovine rotavirus, coronavirus and enteropathogenic E. coli F5 (K99) and reduction of rotavirus and coronavirus shedding by infected calves.

For intramuscular use.

One injection in the course of each pregnancy between the week 12 – 3 before calving is expected.

Feeding of colostrum

The protection of calves depends on adequate ingestion of colostrum from vaccinated cows. Measures should be taken to ensure that calves receive sufficient amounts of colostrum within the first few days of life. It is important that all calves receive sufficient amounts of colostrum within the first six hours after calving. The highest content of antibodies in the colostrum is reached 72 hours after parturition, however absorption of antibodies in the gut of calves is highest within the first 6 – 8 hours after parturition. In the dairy herd, it is recommended that colostrum/milk from the first 6 – 8 milkings of vaccinated mothers is collected and pooled. During the first two weeks of life, the calves must be fed with 2,5 – 3 liters of this pooled colostrum/milk per day.

Shelf-life of the veterinary medicinal product as packaged for sale: 36 months

Store in a refrigerator (2°C – 8°C).